Irritable Bowel Syndrome (IBS) What is IBS? Irritable bowel syndrome (IBS) is a common condition characterized by abdominal discomfort associated with altered bowel movements and is currently diagnosed according to the new Rome IV criteria.Recent research has shown that many symptoms of IBS are related to hypersensitivity of the nerves found in the wall of the gastrointestinal tract. These nerves are distinct from those in your spinal cord and brain. For some people, IBS may arise from how the gut nerves communicate with the brain, or how the brain processes that information. Resources ConstipationConstipation managementDietary fibreDiverticular diseaseFunctional DyspepsiaGastroparesis dietBest management of irritable bowel syndromeNerva app for IBSSAGIS questionnaireLactose intoleranceLow FODMAP dietIBS4GPsAmitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary careDifferentiating between IBS and IBD